![An external file that holds a picture, illustration, etc., usually as some form of binary object. The name of referred object is rmmj-2-1_e0019_Figure2.jpg](images\rmmj-2-1_e0019_Figure2.jpg)
Figure 2.
Predicted model of the active heparanase heterodimer showing the 50 + 8 kDa heparanase subunits, TIM-barrel and C-terminus domains, active site (Glu225 and Glu343, red), and heparin-binding domains (sites A and B). Right: Detailed structure of the C-domain.