An external file that holds a picture, illustration, etc., usually as some form of binary object. The name of referred object is rmmj-3-1-e0002_Figure1.jpg

Figure 1.

A model of the interaction between heparanase (Hepa), TF, and TFPI.

Heparanase interacts with TF resulting in increased generation of factor Xa and enhancement of the coagulation system. Heparanase also up-regulates TF expression and releases TFPI from the cell surface, rendering the cell surface highly procoagulant. TFPI and heparanase may circulate as a complex in the plasma.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2012 January; 3(1): e0002. ISSN: 2076-9172
Published online 2012 January 31. doi: 10.5041/RMMJ.10069.
Copyright : © 2012 Nadir and Brenner