A model for one-stop shop human immune monitoring and a standardized, hospital-driven, immunome project.

(A) Transformative technological advances now enable measurement of multiple parts of the immune system at high bandwidth. Measurement of multiple such modalities from a single sample and their integrated analysis can yield a detailed view of an individual’s immune state which may be informative for clinical decisions. (B) High-resolution analysis of multiple diseases and conditions in a standardized one-stop shop manner allows comparisons across samples and between immune compartments. This will be a bedrock for building a systems-level understanding of the immune system and spear-head a new direction for personalized medicine, more informative than genetic analysis alone.