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Figure 1.

Formation of TRECs.

The whole TCRD gene is interspersed with TCRA gene segments along chromosome 14q11. The D-locus excision forms an episomal DNA circle with a characteristic signal joint DNA region (the so-called sjTREC).

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2014 January; 5(1): e0001. ISSN: 2076-9172
Published online 2014 January 21. doi: 10.5041/RMMJ.10135
Copyright: © 2014 Somech and Etzioni.