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Poster #045, Figure 1:.
qRT-PCR of the Hypertrophic Marker Genes Acta1 (left), Nppa (middle) and Nppb (right) in Neonatal Rat Ventricular Cardiomyocytes, Stimulated to Hypertrophy with Phenylephrine (PE).
Myocytes were infected with control adenovirus Ad-Lacz or adenoviruses encoding for RhoJ WT, RhoJ-DN, and RhoJ CA. Fold expression levels (normalized to GAPDH) are shown, demonstrating suppression of hypertrophy with RhoJ-WT and CA, and no suppression with RhoJ-DN mutant. Serum free medium PE-untreated cells infected with lacz served as control.