Figure 6.
MgSO4 Improves Neonate Learning and Memory Abilities Following Maternal Inflammation.
(A) Demonstration of significant improvement in learning abilities of the NS group, between the first and the third months in almost every block. (B) The LPS group exhibited no significant improvement with time. (C) The MG group displayed significantly better results than the NS group at 1 month of age; however, little improvement was seen at 3 months. (D) Magnesium treatment administered to LPS mothers significantly improved memory and learning abilities at both 1 and 3 months. LPS, lipopolysaccharide; MG, magnesium sulfate; NS, normal saline; 1M, 1 month of age; 3M, 3 months of age. Reprinted from Lamhot et al.,23 Copyright (2015), with permission from Elsevier.
Asterisks (*): Significance (P<0.05) in the learning abilities, examined by the avoidance test in each block between 1 and 3 months.
Blocks (X Axis): Each test comprised 7 blocks of 10 stimulus cycles each. Tests were administered to each rat at 1 and 3 months.
Avoidance (Y Axis): Number of positive avoidance responses in each block.