PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2017 October; 8(4): e0042. ISSN: 2076-9172Published online 2017 October 16. doi: 10.5041/RMMJ.10319.

Table 1.

The Status of Various Paths for Genetically Related Artificial Sperm Production to Date.²⁷

Path	Animal Model			Human
Path	Sperm Cell	Fertilization	Offspring	Sperm Cell	Fertilization	Offspring
In vitro differentiation of germline stem cells	✓	✓	✓
In vitro proliferation of germline stem cells and auto-transplantation	✓	✓	✓
In vitro differentiation of induced pluripotent stem cells	✓			✓
In vitro differentiation of induced pluripotent stem cells and auto-transplantation	✓	✓	✓
In vitro somatic cell transformation into sperm cells
In vivo somatic cell transformation into sperm cells			✓

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2017 October; 8(4): e0042. ISSN: 2076-9172

Published online 2017 October 16. doi: 10.5041/RMMJ.10319