PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2018 July; 9(3): e0019. ISSN: 2076-9172Published online 2018 July 30. doi: 10.5041/RMMJ.10342.

Table 1. Review of NGS Tests in Our Institute

Patient Age (y)	Diagnosis	Genomic Alterations	Potential Therapies	Potential Clinical Trials	VUS	Precision Therapy (mo)	Biological Therapy (mo)	Germline	Patient Status
10;8	Brain	2	3	4	3	0	0	N/A	DOD
11;3	Brain	5	2	7	6	0	0	Y	AWD
17	Brain	2	4	4	4	8	0	N/A	DOD
15	Brain	5	0	4	5	0	0	N/A	AWD
6;5	Brain	3	2	4	0	14	0	Y	DOD
7;6	Brain	4	2	8	12	0	0	N/A	DOD
8;6	Brain	1	3	2	6	0	0	N/A	AWD
15;2	Colon carcinoma	4	2	11	7	0	0	Suspected	DOD
16;8	Colon carcinoma	67	14	39	52	0	0	Y	AWD
14;11	Ewing	1	0	0	8	0	0	N/A	DOD
18;1	Ewing	4	0	0	3	0	0	N/A	DOD
19;2	Ewing	3	2	4	7	0	0	Suspected	AWD
13	Germ cell	3	8	7	5	0	0	Suspected	NED
3	Hepatoblastoma	1	0	10	8	0	5	N/A	AWD
13;7	Neuroblastoma	3	5	5	15	0	0	N/A	DOD
10	Neuroblastoma	1	0	0	10	0	0	N/A	AWD
9	Neuroblastoma	0	0	0	9	0	0	N/A	DOD
7;8	Neuroblastoma	2	2	8	14	5	0	N	DOD
1;8	Neuroblastoma	1	0	7	4	0	0	N/A	NED
1;4	Neuroblastoma	6	0	0	12	0	0	N/A	AWD
2;7	Neuroblastoma	2	0	4	17	0	0	N/A	DOD
20	Osteosarcoma	8	4	15	9	0	6	Y	DOD
15.3	Osteosarcoma	5	2	6	10	0	0	N/A	DOD
13;3	Osteosarcoma	7	0	8	10	0	5	N/A	DOD
12;9	Osteosarcoma	4	0	0	16	0	0	N/A	DOD
15;5	Osteosarcoma	1	0	0	11	0	0	Suspected	AWD
17;4	Other	1	0	0	10	0	0	N/A	AWD
1;6	Other	1	1	0	9	0	0	N/A	DOD
12;2	Other	0	0	0	12	0	0	N/A	AWD
0;9	Rhabdoid	1	0	6	7	0	0	N/A	NED
12;5	RMS	2	0	4	10	0	4	N/A	DOD
19;6	RMS	3	0	0	13	0	7	N/A	AWD
4;9	RMS	2	0	0	12	0	8	Suspected	DOD
9	RMS	3	2	5	13	0	6	Suspected	DOD
5	Wilms’s	1	0	4	7	0	0	N/A	NED
6;4	Wilms’s	2	0	2	9	0	0	N/A	DOD
6;4	Wilms’s	3	0	2	9	0	4	N/A	DOD

AWD, alive with disease; DOD, dead of disease; mo, months of therapy; N, non-approved; N/A, not available; NED, no evidence of disease; RMS, rhabdomyosarcoma; Suspected, in case of positive family history or suspected mutation; Y, yes, approved.