Liver Biopsy at First Evaluation and Repeated Biopsy Four Years Later.

A liver needle biopsy taken within the first evaluation showed preserved lobular architecture (A, HE 4×) and mild portal inflammation with several eosinophils seen in the infiltrate (B, HE 40×). Masson trichrome stain showed focal bridging fibrosis (C, trichrome 4×). A second biopsy taken four years later showed portal inflammation (D, HE 4×) with fewer eosinophils in the infiltrates (E, HE 40×) and no change in fibrosis (F, trichrome 4×). White arrowheads indicate eosinophils.