Elastic Fiber Parameters for Varying Grades of Oral Squamous Cell Carcinoma (OSCC) and Epithelial Dysplasia.
Elastic Fiber Parameters for Varying Grades of Oral Squamous Cell Carcinoma (OSCC) and Epithelial Dysplasia.
Fiber Parameter | Chi-square (P value) | Mild Dysplasia (n=20) | Moderate Dysplasia (n=20) | Severe Dysplasia (n=20) | Well-diff. OSCC (n=20) | Moderately Diff. OSCC (n=20) | Poorly Diff. OSCC (n=20) |
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Elastic fiber density | 114.33 (<0.001) | ||||||
Scanty | – | 4 | 20 | 12 | – | 20 | |
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Moderate | 18 | 16 | – | 8 | 6 | – | |
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Abundant | 2 | - | 6 | - | 14 | – | |
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Morphology | 120.00 (<0.001) | ||||||
Short, thick, wavy | 20 | 20 | - | 20 | 20 | – | |
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Long, thin, straight | - | - | 20 | - | - | 20 | |
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Grouping pattern | 10.17 (0.071) | ||||||
Single | 18 | 20 | 20 | 20 | 20 | 20 | |
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In bunches | 2 | – | - | - | - | - | |
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Staining intensity | 93.9 (<0.001) | ||||||
Weak | 14 | 2 | 2 | 2 | – | 2 | |
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Moderate | 2 | 12 | 16 | 16 | 4 | 16 | |
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Strong | 4 | 6 | 2 | 2 | 16 | 2 | |
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Orientation to overlying epithelium | 75.16 (<0.001) | ||||||
Parallel | 20 | 20 | – | 16 | 14 | 4 | |
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Perpendicular | – | – | 20 | 4 | 6 | 16 | |
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Orientation to tumor islands | 20.04 (<0.001) | ||||||
Parallel | NA | NA | NA | 18 | 6 | 4 | |
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Haphazard | NA | NA | NA | 2 | 14 | 16 |