Weighted ASD Diagnostic Power for Each Evaluated Modality.
Weighted ASD Diagnostic Power for Each Evaluated Modality.
Modality | Sensitivity (%) | Specificity (%) | Overall Agreement (%) | Area under Curve (AUC) (%) |
---|---|---|---|---|
Genetic | ||||
Pool | 79.3 | 73.1 | 76.7 | 79.5 |
Range | 24.3–100 | 41.8–88.2 | 62.7–90.4 | 64.8–92.0 |
95% CI | 73.3–84.7 | 69.6–76.5 | 73.8–79.5 | 77.0–82.0 |
I2 | 87.5 | 56.9 | 70.8 | 52.5 |
| ||||
MRI | ||||
Pool | 73.6 | 73.0 | 73.5 | 79 |
Range | 43.7–94.8 | 45.4–100 | 57.9–95.7 | 58.0–99.5 |
95% CI | 71.8–76.0 | 70.0–76.0 | 71.0–75.9 | 75.0–83.0 |
I2 | 78.1 | 84.4 | 89.1 | 96.4 |
| ||||
Metabolic | ||||
Pool | 74.6 | 85.9 | 83.3 | 88.3 |
Range | 0–100 | 15.0–100 | 48.7–100 | 59.2–99.9 |
95% CI | 66.8–81.6 | 82.7–88.7 | 80.3–86.1 | 86.0–91.0 |
I2 | 97.7 | 87.1 | ND | 92.2 |
| ||||
Protein | ||||
Pool | 85.5 | 84.7 | 83.8 | 89.5 |
Range | 50–100 | 38.9–100 | 62.8–100 | 57.0–99.9 |
95% CI | 80.0–90.3 | 78.6–90 | 81.0–86.5 | 86.0–93.0 |
I2 | 87.3 | 89.2 | 73 | 90.1 |
| ||||
EEG | ||||
Pool | 79.9 | 80.4 | 79.9 | ND |
Range | 57.6–90.9 | 64.5–100 | 70.5–87.4 | ND |
95% CI | 70.5–87.9 | 73.3–86.6 | 73.5–85.5 | ND |
I2 | 83.4 | 79.5 | 85.2 | ND |