PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2023 January; 14(1): e0002. ISSN: 2076-9172Published online 2023 January 29. doi: 10.5041/RMMJ.10489.

Table 1.

Bleeding, Hematocrit Loss, and Mortality in Immediate Survivors Undergoing Combined Injury (bTBI+UCHS), Uncontrolled Hemorrhagic Shock (UCHS), or bTBI only.

Group Name	No. of Rats	Mean Blood Loss Until Resuscitation (95% CI)	Mean Blood Loss^* After Start of Resuscitation (95% CI)	Hematocrit Loss^* Between Baseline and 45 min (95% CI)	Mean Hematocrit at 120 min (95% CI)	Mortality Proportion (95% CI)
Sham	11	N/A	N/A	3.7 (2.1, 5.4)	39.5 (37.7, 41.3)	0.00 (0.00, 0.30)
bTBI	10	N/A	N/A	4.9 (2.2, 7.6)	38.5 (35.0, 42.1)	0.20 (0.50, 0.52)

UCHS	16	1.6 (0.4, 2.8)	1.7 (0, 4.0)	7.9 (6.8, 9.0)	35.5 (33.4, 37.6)	0.44 (0.23, 0.67)
UCHS+LR	11	1.9 (1.2, 2.7)	1.4 (0.3, 2.6)	8.3 (7.0, 9.6)	35.6 (33.2, 38.0)	0.36 (0.15, 0.65)
UCHS+FFP	11	1.7 (1.0, 2.5)	3.1 (1.1, 5.0)	10.5 (8.5, 12.4)	32.1 (29.4, 34.8)	0.36 (0.15, 0.65)

bTBI+UCHS	14	2.1 (0.7, 3.5)	1.9 (0, 3.9)	9.3 (7.6, 11.0)	38.5 (32.6, 44.4)	0.64 (0.39, 0.84)
bTBI+UCHS+LR	12	1.7 (1.3, 2.2)	2.5 (1.2, 3.8)	9.5 (7.6, 11.4)	36.4 (31.6, 41.2)	0.42 (0.19, 0.68)
bTBI+UCHS+FFP	12	2.3 (1.8, 2.7)	5.2 (3.7, 6.6)	13.5 (11.9, 15.1)	31.8 (27.8, 35.7)	0.83 (0.54, 0.97)

^*Missing data in 7 rats.

bTBI, blunt traumatic brain injury; CI, confidence interval; FFP, fresh frozen plasma; LR, lactated Ringer’s solution; N/A, not applicable; UCHS, uncontrolled hemorrhagic shock.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2023 January; 14(1): e0002. ISSN: 2076-9172

Published online 2023 January 29. doi: 10.5041/RMMJ.10489